Our family has been (mostly) failsafe since our older son was diagnosed with autism and multiple food intolerance in 2003.
Last year for some months I was allowing a chocolate coated icecream on a stick containing annatto 160b, once a week I bought a box to share with the kids after shopping.
I had thought it would be ok as our very food sensitive older son didn't react noticeably to the 160b challenge.
Our now 5 year old younger son's behaviour rapidly went downhill until he was a truly horrible little boy, who physically attacked his siblings, flew off the handle at the slightest little thing, roaring and shaking with anger, things were broken in our house including a glass door and a bucket over his brother's head which drew blood! The behaviour followed a pattern each week of a couple of truly horrible days slowly getting less awful over the course of a week. So I had already figured out it was a food eaten once a week, around shopping day, but still hadn't thought of the icecream. Of course as soon as I woke up to it, the icecream was out the door, and our lovely boy and calm home returned. I've since tested annatto 160b a few times both deliberately and accidently and the horrible week long rage returned. Annatto 160b would have to be one of our family's most hated baddies! - Karen, Qld